Ubiquinone is the form of CoQ10 used by Biotics Research. It is the stable form and is the form synthesized by the body.
Ubiquinol is a reduced form of CoQ10. It is unstable, and therefore must be supplied as a softgel or a low concentrated micro-encapsulation.
Some would suggest that the body cannot convert Ubiquinone to Ubiquinol. The fact is, Ubiquinone converts back and forth to Ubiquinol…This is how the electrons get transported; the molecule gains an electron and forms Ubiquinol, and losses and electron to form Ubiquinone. This is why it’s called “redox” (reduction is the addition of an electron, and oxidation is the loss of an electron).
Ubiquinol was found to improve congestive heart failure (CHF) in subjects at doses pf 900 mg per day. However, the study’s author, Peter Langsjoen (Biofactors 32, 2008) reported that it was the plasma level of CoQ10 that favored the clinical outcome. In an interview with Kirk Hamilton, he reported “Many patients absorb CoQ10 quite well and if they are doing well with a good plasma level on Ubiquinone, there is no reason to switch to Ubiquinol. Our practice is to use supplemental CoQ10 in all patients with impaired heart muscle function”.
Biotics’ micro-emulsified CoQ10 (Ubiquinone), unlike the typical dry powder form that was the source of comparison by Ubiquinol, has demonstrated uptake and bioavailability 3 times greater than the dry form, is more cost effective than Ubiquinol, and because it is stable, can be supplied in more dose forms (tablets, capsules, powders, liquids).
Biotics Research was the first company to introduce CoQ10 as a dietary supplement back in the early 1980s. Back then, it was only available in Japan as a pharmaceutical preparation and was not available for export. Therefore, Biotics Research produced our own CoQ10 as a concentrated extract from bovine heart tissue. Today, Coenzyme Q10 is produced in many countries via chemical synthesis or micro-fermentation process. Biotics Research only uses fermented CoQ10 material in our products.
Biotics’ emulsified CoQ10 contains no soy derivatives, artificial detergents or chemical surfactants such as polyoxyethylenesorbintan ester (Tween 80) or polyethylene glycol; all of which are commonly used to enhance CoQ absorption into the blood by making it “water soluble”. Biotics’ emulsified QoQ10 is not water soluble, but is micro-emulsified into tiny microscopic droplets and is water dispersible. Biotics’ emulsified CoQ10 is absorbed lymphatically, as Mother Nature intended, and transports in the lymph, where it appears in the abdominal lymph duct in 2-3 hours, and peaks in the venous blood in 6 to 8 hours.